Slideshows are usually talkative, so it's not surprising that you sometimes need to pause the sound during the presentation. With PowerPoint you can do this with one click.
Stopping audio during a presentation
If your presentation is not intended for a speaker (for example, a slideshow full of pictures that an audience can watch during a wedding) it's probably at a point where you have to pause the sound to answer questions, talk longer about a topic than intended, and so on. Luckily, pausing audio is extremely easy.
Open the presentation that you will work with. Continue and insert your audio if you have not already done so.
When you're done, start with your presentation. To do this, in the Start Slideshow section of the Slide Show tab, choose From Beginning. You can also press the F5 key.
You will find the audio icon on the slide that contains the audio file.
Hovering over the audio icon will display a progress bar for the audio file along with a volume knob and a play / pause button. Click the pause button to pause the sound.
Alternatively, press Alt + P to pause and resume the sound.
That's all that goes with it. The downside is that this option is not available if you're continuously playing the audio through the slideshow or hiding the audio icon (although you can still use the Alt + P keyboard shortcut), then plan your presentation accordingly.